What is the primary goal of using prostaglandins and corticosteroids to lyse corpora lutea in a sow 30-48 days into gestation?

What is the primary goal of using prostaglandins and corticosteroids to lyse corpora lutea in a sow 30-48 days into gestation?

• A. Luteolysis to terminate pregnancy
• B. Stimulate lactation
• C. Promote growth
• D. Increase fertility

Answer: (A)

The essential idea is that keeping a sow pregnant at this stage depends on progesterone produced by the corpus luteum. Prostaglandin F2 alpha directly targets the luteal tissue to cause luteolysis, so the CL stops producing progesterone. Without progesterone, the uterine environment can no longer support the pregnancy, leading to abortion. Corticosteroids help by suppressing the signals that keep the CL active (such as LH support), speeding luteal regression and reinforcing the abortion when used with prostaglandin. This combination specifically aims to terminate the pregnancy, not to enhance lactation, growth, or fertility.

The essential idea is that keeping a sow pregnant at this stage depends on progesterone produced by the corpus luteum. Prostaglandin F2 alpha directly targets the luteal tissue to cause luteolysis, so the CL stops producing progesterone. Without progesterone, the uterine environment can no longer support the pregnancy, leading to abortion. Corticosteroids help by suppressing the signals that keep the CL active (such as LH support), speeding luteal regression and reinforcing the abortion when used with prostaglandin. This combination specifically aims to terminate the pregnancy, not to enhance lactation, growth, or fertility.